Otto-von-Guericke-Universität Magdeburg



Grimm D., Grosse J, Wehland M., Mann V., Reseland J.E., Sundaresan A., Corydon J. "The impact of microgravity on bone in humans." Bone 2015 (paper accepted)

Wehland M, Warnke E, Frett T, Hemmersbach R, Hauslage J, Ma X, Alehcheva G, Pietsch J, Bauer J, Grimm D. "The impact of microgravity and vibration on gene and protein expression of thyroid cells." Microgravity Sci. Technol. 2015 (paper accepted)

Corydon JT, Kopp, S, Wehland M, Braun M, Schütte A, Mayer T, Hülsing T, Oltmann H, Schmitz B, Hemmersbach R, Grimm D. "Alterations of the cytoskeleton in human cells in space proved by life-cell imaging." Sci Rep. 2016 Jan 28;6:20043

Andersen MB, Simonsen U, Wehland M, Pietsch J, Grimm D. "LCZ696 (Valsartan/Sacubitril) - A possible new treatment for hypertension and heart failure." Basic Clin Pharmacol Toxicol. 2016 Jan;118(1):14-22

Aleshcheva G., Bauer J., Hemmersbach R., Egli M., Wehland M., Grimm D. "Tissue engineering of cartilage on ground-based facilities." Microgravity Sci. Technol. 2015 (paper accepted) DOI 10.1007/s12217-015-9479-0

Bauer J., Wehland M., Pietsch J., Sickmann A., Weber G., Grimm D. "Annotated gene and proteome data support recognition of interconnections between the results of different experiments in space research." Microgravity Sci. Technol. 2015 (Epub ahead of print) DOI 10.1007/s12217-015-9451-z

Warnke E., Kopp S., Wehland M., Hemmersbach R., Bauer J., Pietsch J., Infanger M., Grimm D. "Thyroid cells exposed to simulated microgravity conditions? Comparison of the fast rotating clinostat and the Random Positioning Machine." Microgravity Sci. Technol. 2015 (Epub ahead of print) DOI: 10.1007/s12217-015-9456-7

Riwaldt S., Bauer J., Pietsch J., Braun M., Segerer J., Schwarzwälder A., Corydon T.J., Infanger M., Grimm D. "The Importance of Caveolin-1 as Key-Regulator of Three-Dimensional Growth in Thyroid Cancer Cells Cultured under Real and Simulated Microgravity Conditions." Int J Mol Sci. 2015 Nov 30;16(12):28296-310

Kopp S., Warnke E, Wehland M., Aleshcheva G., Magnusson N.E., Hemmersbach R., Juhl Corydon T., Bauer J., Infanger M., Grimm D. "Mechanisms of three-dimensional growth of thyroid cells during long-term simulated microgravity." Sci Rep. 2015 Nov 18;5:16691

Svejgaard B., Wehland M., Ma X., Kopp S., Sahana J., Warnke E., Aleshcheva G., Hemmersbach R., Hauslage J., Grosse J., Bauer J., Corydon TJ, Islam T, Infanger M, Grimm D. "Common effects on cancer cells exerted by a Random Positioning Machine and a 2D Clinostat." PLoS One. 2015;10:e0135157.

Riwaldt S, Pietsch J, Sickmann A, Bauer J, Braun M, Segerer J, Schwarzwälder A, Aleshcheva G, Corydon T.J., Infanger M., Grimm D. "Identification of proteins involved in inhibition of spheroid formation under microgravity." Proteomics. 2015;15:2945-52

Wehland M., Aleshcheva G., Schulz H., Saar H., Hübner N., Hemmersbach R., Braun M., Ma X., Frett T., Warnke E., Riwaldt S., Pietsch J., Corydon T.J., Infanger M., Grimm D.: "Differential gene expression of human chondrocytes cultured under short-term altered gravity conditions during parabolic flight maneuvers." Cell Commun Signal. 2015;13:18

Fisker F.Y., Grimm D., Wehland M.: "Third-generation beta-adrenoceptor antagonists in the treatment of hypertension and heart failure." Basic Clin Pharmacol Toxicol. 2015;117:5-14

Aleshcheva G., Wehland M., Sahana J., Bauer J., Corydon T.J., Hemmersbach R., Frett T., Egli M., Infanger M., Grosse J., Grimm D.: "Moderate alterations of the cytoskeleton in human chondrocytes after short-term microgravity produced by parabolic flight maneuvers could be prevented by up-regulation of BMP-2 and SOX-9." FASEB J. 2015;29:2303-14.

Wuest S.L., Richard S., Kopp S., Grimm D., Egli M.: "Simulated Microgravity: Critical Review on the Use of Random Positioning Machines for Mammalian Cell Culture." Biomed Res Int. 2015;2015:971474.

Kristensen T.B., Knutsson M.L., Wehland M., Laursen B.E., Grimm D., Warnke E., Magnusson N.E.: "Anti-Vascular Endothelial Growth Factor Therapy in Breast Cancer." Int J Mol Sci. 2014;15:23024-23041.

Nielsen O.H., Grimm D., Wehland M., Bauer J., Magnusson N.E.: "Anti-Angiogenic Drugs in the Treatment of Metastatic Renal Cell Carcinoma: Advances in Clinical Application." Curr Vasc Pharmacol. 2015;13:381-91.

Ulbrich C., Wehland M., Pietsch J., Aleshcheva G., Wise P., van Loon J., Magnusson N., Infanger M., Grosse J., Eilles C., Sundaresan A., Grimm D.: "The impact of simulated and real microgravity on bone cells and mesenchymal stem cells." Biomed Res Int. 2014;2014:928507. doi: 10.1155/2014/928507.

Grimm D., Pietsch J., Wehland M., Richter P., Strauch S.M., Lebert M., Magnusson N.E., Wise P., Bauer J.: "The impact of microgravity-based proteomics research." Expert Rev Proteomics. 2014;11:465-476.

Grimm D., Wehland M., Pietsch J., Aleshcheva G., Wise P., van Loon J., Ulbrich C., Magnusson N.E., Infanger M., Bauer J.: "Growing Tissues in Real and Simulated Microgravity: New Methods for Tissue Engineering." Tissue Eng Part B Rev. 2014;20:555-66.

Warnke E., Pietsch J., Wehland M., Bauer J., Infanger M., Görög M., Hemmersbach R., Braun M., Ma X., Sahana J., Grimm D.: "Spheroid formation of human thyroid cancer cells under simulated microgravity: a possible role of CTGF and CAV1." Cell Commun Signal. 2014;12:32.

Ma X., Sickmann A., Pietsch J., Wildgruber R., Weber G., Infanger M., Bauer J., Grimm D.: "Proteomic differences between microvascular endothelial cells and the EA.hy926 cell line forming three-dimensional structures." Proteomics. 2014;14:689-698.

Grosse J., Warnke E., Wehland M., Pietsch J., Pohl F., Wise P., Magnusson N.E., Eilles C., Grimm, D.: "Mechanisms of apoptosis in irradiated and sunitinib-treated follicular thyroid cancer cells." Apoptosis. 2014;19:480-490.

Wildgruber R., Weber G., Wise P., Grimm D., Bauer J.: "Free flow electrophoresis in proteome sample preparation." Proteomics. 2014;14:629-636.

K. Harth, T. Trittel, K. May, S. Wegner, R. Stannarius "Three-dimensional (3D) experimental realization and observation of a granular gas in microgravity" Adv. Space Res. 55 1901 (2015)

S. Dölle, K. Harth, T. John, R. Stannarius, "Impact and Embedding of Picoliter Droplets into Freely Suspended Smectic Films" Langmuir 30 12712 (2014)

K. May, K. Harth, T. Trittel, R. Stannarius "Freely floating smectic films" ChemPhysChem 15 1508 (2014)

Thiel, C.S., Tauber, S., Schütte, A., Schmitz, B., Nuesse, H., Moeller, R., Ullrich, O. "Functional Activity of Plasmid DNA after Entry into the Atmosphere of Earth Investigated by a New Biomarker Stability Assay for Ballistic Spaceflight Experiments" PLoS ONE 9(11): e112979. doi:10.1371/journal.pone.0112979 (2014)

Katrin Paulsen, Svantje Tauber, Claudia Dumrese, Ullrich, O. et al. “Regulation of ICAM-1 in Cells of the Monocyte/Macrophage System in Microgravity,” BioMed Research International, Article ID 538786, in press. (2014)

Thiel, C.S., Hauschild, S., Tauber, S., Paulsen, K., Raig, C., Raem, A., Biskup, J., Gutewort, A., Hürlimann, E., Unverdorben, F., Buttron, I., Lauber, B., Philpot, C., Lier, H., Engelmann, F., Layer, L.E., Ullrich, O. "Identification of Reference Genes in Human Myelomonocytic Cells for Gene Expression Studies in Altered Gravity" BioMed Research International, Article ID 363575, in press. (2014)

Hauschild, S., Tauber, S., Lauber, B., Thiel, C.S., Layer, L.E., Ullrich, O. "T cell regulation in microgravity – The current knowledge from in vitro experiments conducted in space, parabolic flights and ground-based facilities" Acta Astronautica 104 (2014) 365-377

Adrian, A., Schoppmann, K., Sromicki, J., Brungs, S., von der Wiesche, M., Hock, B., Kolanus, W., Hemmersbach, R., Ullrich, O. "The oxidative burst reaction in mammalian cells depends on gravity." Cell Commun Signal. 2013, 11:98

Herranz, R., Anken, R., Boonstra, J., Braun, M., Christianen, P.C.M., de Geest, M., Hauslage, J., Hilbig, R., Hill, R.J.A., Lebert, M., Medina, F.J., Vagt, N., Ullrich, O., van Loon, J.W.A., Hemmersbach, R. "Ground-based facilities for simulation of microgravity: organism-specific recommendations for their use, and recommended terminology." Astrobiology 2013, 13(1): 1-17

Tauber, S., Hauschild, S., Crescio, C., Secchi, C., Paulsen, K., Pantaleo, A., Saba, A., Buttron, I., Thiel, C.S., Cogoli, A., Pippia, P., Ullrich, O.
  "Signal transduction in primary human T lymphocytes in altered gravity - results of the MASER-12 suborbital space flight mission." Cell Commun Signal. 2013, 11(1):32

Simmet, D.M., Schwarzwälder, A., Paulsen, K., Tauber, S., Engelmann, F., Thiel, C., Ullrich, O. "Biotechnology for the investigation of the monocyte-macrophage-system in microgravity and space." Recent Advances in Space Biotechnology 2013, 3, 48-63

Ullrich, O., Graf, J. "Im Auftrag für Medizin und Forschung. Spezialtransporte an Bord von Luftfahrzeugen."
Flugmedizin Tropenmedizin Reisemedizin 2013
, 20(5): 248-254

Harth, K., Kornek, U., Trittel, T., Strachauer, U., Höme, S., Will, K., Stannarius, R. "Granular Gases of Rod-Shaped Grains in Microgravity."
Phys. Rev. Lett. 2013,
110, 144102

Harth, K., Trittel,T., Kornek, U., Höme, S., Will, K.,  Strachauer, U., Stannarius, R. "Microgravity experiments on a granular gas of elongated grains"
AIP Conf. Proc. 2013,
1542, 807

Paulsen, K., Tauber, S., Gölz, N., Simmet, D.M., Engeli, S., Birlem, M., Dumrese, C., Karer, A., Hunziker, S., Biskup, J., Suh, D., Hürlimann, E., Signer, C., Wang, A., Sang, C., Grote, K.-H., Zhuang, F., Ullrich, O. "Severe disruption of the cytoskeleton and immunologically relevant surface molecules in a human macrophageal cell line in microgravity ? Results of an in vitro experiment on board of the Shenzhou-8 space mission." Acta Astronautica, 2014, 94(1), 277-292

Ma, X., Pietsch. J., Wehland, M., Schulz, H., Saar, K., Hübner, N., Bauer, J., Braun, M., Schwarzwälder, A., Segerer, J., Birlem, M., Horn, A., Hemmersbach, R., Wasser, K., Grosse, J., Infanger, M., Grimm, D. “Differential gene expression profile and altered cytokine secretion of thyroid cancer cells in space.” FASEB J 2014, 28(2): 813-835 

Aleshcheva, G., Sahana, J., Ma, X., Hauslage, J., Hemmersbach, R., Egli, M., Infanger, M., Bauer, J., Grimm, D. “Changes in morphology, gene expression and protein content in chondrocytes cultured on a random positioning machine.” PLoS One 2013, 8(11): e79057

Grimm, D., Bauer, J., Hemmersbach, R., Ulbrich, C., Pietsch, J., Wehland, M., Infanger, M. „Biotechnological use of weightlessness for medical research -analysis of human cells after weightlessness.” Flug u Reisemed 2013, 20(4): 173-178

Pietsch, J., Ma, X., Wehland, M., Aleshcheva, G., Schwarzwälder, A., Segerer, J., Birlem, M., Horn, A., Bauer, J., Infanger, M., Grimm, D. “Spheroid formation of human thyroid cancer cells in an automated culturing system during the Shenzhou-8 Space mission.” Biomaterials 2013, 34(31): 7694-7670

Ma, X., Wehland, M., Aleshcheva, G., Hauslage, J., Wasser, K., Hemmersbach, R., Infanger, M., Bauer, J., Grimm, D. “Interleukin-6 Expression under Gravitational Stress Due to Vibration and Hypergravity in Follicular Thyroid Cancer Cells. “ PLoS One 2013, 8(7): e68140

Ma, X., Wehland, M., Schulz, H., Saar, K., Hübner, N., Infanger, M., Bauer, J., Grimm, D. “Genomic approach to identify factors that drive the formation of three-dimensional structures by EA.hy926 endothelial cells.” PLoS One 2013, 8(5): e64402

Wehland, M., Ma, X., Braun, M., Hauslage, J., Hemmersbach, R., Bauer, J., Grosse, J., Infanger, M., Grimm, D. „The impact of altered gravity and vibration on endothelial cells during a parabolic flight.” Cell Physiol Biochem 2013, 31(2-3): 432-451

Pietsch, J., Riwaldt, S., Bauer, J., Sickmann, A., Weber, G., Grosse, J., Infanger, M., Eilles, C., Grimm, D. „ Interaction of proteins identified in human thyroid cells.” Int J Mol Sci 2013, 14(1): 1164-1178

Ma, X., Sickmann, A., Pietsch, J., Wildgruber, R., Weber, G., Infanger, M., Bauer, J., Grimm, D. „Proteomic differences between microvascular endothelial cells and the EA.hy926 cell line forming three-dimensional structures.” Proteomics 2013, 26. doi: 10.1002/pmic.201300453. [Epub ahead of print]

Grosse J., Warnke E., Pohl F., Magnusson N.E., Wehland M., Infanger M., Eilles C., Grimm D. "Impact of sunitinib on human thyroid cancer cells." Cell Physiol Biochem. 2013;32:154-170.

Wehland M, Bauer J, Magnusson NE, Infanger M, Grimm D. "Biomarkers for anti-angiogenic therapy in cancer." Int J Mol Sci. 2013;14:9338-9364.




Letzte Änderung: 03.02.2016 - Ansprechpartner: Webmaster
Prof. Dr. Ralf Stannarius

Fakultät für Naturwissenschaften
Abteilung Nichtlineare Phänomene

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Universitätsplatz 2
39106 Magdeburg

Tel: 0391-67-58582
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